Posted on Thu, 05 Feb 2026 11:00:00 +0000

Worms to the Rescue: Separating the Good, the Bad, and the Clumpy Huntingtin

⏱️ 7 min read | A team of researchers developed a simple platform to test how toxic different types of HTT protein clumps are using a laboratory worm model. They showed that certain types of clumps are harmful to the worms, while others are not.

From: HDBuzz

Posted on Mon, 02 Feb 2026 10:43:16 +0000

January 2026: This Month in Huntington’s Disease Research

⏱️ 9 min read | January 2026 HD research recap: SKY-0515 shows promising safety data, community advocacy helps secure critical FDA meeting for AMT-130, plus new insights on sleep, vaccines, and symptom management. Read the full roundup!

From: HDBuzz

Posted on Wed, 28 Jan 2026 20:07:35 +0000

Phase 1 results announced for Skyhawk’s drug SKY-0515

Skyhawk Therapeutics shared results for SKY-0515, a drug designed to lower huntingtin. The drug appeared generally safe, with 60% reduction of huntingtin in blood at the highest dose tested. This data is an encouraging step as larger trials continue.

From: HDBuzz