⏱️8 min read | Scientists have known that MutLβ is linked to repeat expansion but not exactly how. A study reveals that the MutLβ protein complex is a main player supporting and interacting with key DNA repair proteins to drive DNA repeat expansions.

⏱️8 min read | Scientists screened over a trillion tiny ring-shaped protein fragments to find ones that can grab onto the huntingtin. They captured huntingtin straight out of cells and discovered it’s almost always paired with a partner called HAP40.

⏱️6 min read | A new study suggests that reduced awareness of symptoms, known as anosognosia, may appear even in the earliest stages of HD. The findings highlight that understanding symptom progression requires more than one perspective.